With Z Fill, there is now an effective and long-lasting way to regain a youthful and fresh appearance, add volume and treat wrinkles.

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Product Details
Technical specifications

Proven quality "made in Europe"

The three hyaluronic acid fillers of the Z-Fill series are manufactured according to strict European quality and safety standards. They comply with ISO 9001, ISO 13485 and GMP (Good Manufacturing Practice) standards and guidelines. Toxicological studies and biological compatibility tests are performed in accordance with the ISO 10993 series of standards.

100 % degradable
Thanks to an innovative, multi-stage production process, the gels gain maximum stability. This slows down the body's own breakdown processes and guarantees a long-term effect. Immediately after hyaluronic acid therapy, a rejuvenating effect is noticeable. Z-Fill permanently activates the revitalization of aging skin. It compensates for the age-related hyaluronic acid deficiency and systematically hydrates the dermis.

Highest purity for maximum safety
Connections: The addition of BDDE creates cross-links between the hyaluronic acid chains. A very dense, three-dimensional matrix is formed and the gel gains stability and resistance to skin breakdown processes. - This explains the long-lasting effect of Z-Fill contour2 and Z-Fill deep2.

The preparation is then homogenized. The gel is now sticky yet extremely flexible and elastic - ideal for even and controlled injection with thin needles.

A complex cleaning procedure follows. All unnecessary and harmful components (unbound BDDE, proteins and endotoxins) are carefully removed. The result is exceptional purity that far exceeds the strict requirements of the European Medical Device Directive.

The oxygen is then removed from the gel, making it even more stable and durable.

In the final step, the filled gel syringes are sterilized in a steam autoclave.

To ensure that the syringes are free of particles, each individual syringe is subjected to a visual inspection. Only after the necessary production and safety tests according to the latest European standards is the respective Z-Fill batch released.

Lip volume before treatment and after 14 days.


Nasolabial before treatment and after 14 days.


Labial angle before treatment and after 14 days.


Scar treatment before and after 14 days.


Your questions, our answers

What treatments can be performed with Z Fill products?
The Z-Fill product line is suitable for general skin refreshment to the treatment of deep wrinkles, volume building and lip filling:

  • Regeneration and replenishment of skin hyaluronic acid levels
  • Improvement of elasticity
  • Volume accumulation with age-related volume loss due to age loss
  • Treatment of fine, medium and deep wrinkles, glabellar wrinkles, nasolabial wrinkles and nose and ear wrinkles
  • Lip filler

When will the effect be visible?

Results are visible immediately after treatment and are further enhanced in the following weeks thanks to the stimulation of collagen regeneration.

How long does the effect last?
Thanks to the innovative Z-Fill technology, the effect lasts up to 18 months. Thanks to its special composition, Z-Fill ensures a particularly long-lasting effect. Z Fill Refresh can be used at any time to refresh the skin.

How long does the treatment last?
The duration depends on the area to be treated and takes between 15 and 30 minutes.

What happens during treatment?
Your doctor injects the Z-Fill preparation directly into the skin with a very fine needle. Depending on the area to be treated, the injection takes place very superficially or in the deeper layers of the skin.

Is the treatment painful?
Thanks to the gel-like substance of the Z-Fill preparations, the injection is extremely gentle and thus painless. Depending on the individual pain sensation, treatment with cold air can be performed before and after the treatment. This has been shown to reduce pain. Ask your doctor about this treatment option. A numbing ointment and cooling gel can also be used.

What should I pay attention to after treatment?
You can resume your normal daily routine immediately after treatment. Within the first 10 days after treatment, sunbathing, solarium and sauna visits, and laser and IPL treatments should be avoided.

Can side effects occur?
Allergic reactions are virtually impossible due to the non-animal origin of Z-Fill preparations. After injection, slight redness and swelling may occur initially, but it disappears after a short time.

The low pain concept Z-Fill
To achieve optimal treatment results, the products, like all conventional injectable implants, must be carefully but quickly injected into the middle dermis.

Studies have shown that cooling with the Cryo 6 cold air device reduces patients' sensitivity to pain. This means that the treatment is much better tolerated. After the procedure, the treated area is massaged with light pressure to ensure even distribution of the product.

The mimic muscles should be used as little as possible until 2 hours after treatment to facilitate integration of the implant into the surrounding cellular network. Short-term cooling of the treated area can further reduce the occurrence of swelling and redness.

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